Levitra

The effectiveness of Levitra for potency. Where to get Vardenafil online?

Vardenafil online

Content:

The effectiveness of the drug Levitra for potency. Where to get Vardenafil online?

The effectiveness of the drug Levitra for potency

«Levitra» – One of the most popular treatments for erectile disfunction today. Vardenafil, a member of the PDE5 inhibitor group, restores the sensitivity of the penis and resumes the natural response to sexual arousal.

It is produced in Germany at the factories of Bayer Schering Pharma, which is part of the world-famous pharmaceutical concern Bayer AG.

The composition of the drug

Active ingredient «Levitra» favored by the Vardenafil. More specifically, Vardenafil Hydrochloride, which share in one tablet, depending on the form of release and dosage, is 5.926 mg, 11.852 mg or 23.705 mg (which corresponds to 5 mg, 10 mg or 20 mg of pure Vardenafil, respectively).

As for excipients, their dosage in the preparation will be more conveniently presented in the form of a table.

The effectiveness of the drug Levitra for potency. Where to get Vardenafil online?
At 5 mg Vardenafil 10 mg Vardenafil At 20 mg Vardenafil
Kernel auxiliaries
Colloidal anhydrous silica 435 mcg 625 mcg 885 mkg
Crospovidone 4.35 mg 6.25 mg 8.85 mg
Microcrystalline cellulose 75.419 mg 105.023 mg 141.797 mg
Magnesium stearate 870 mcg 1.25 mg 1.77 mg
Auxiliary substances that are part of the shell
Hypromellose 1,664 mg 2.391 mg 3,385 mg
Titanium dioxide 455 mcg 653 mcg 925 mcg
Yellow iron oxide 92 mcg 133 mcg 188 mcg
Red iron oxide 7 mcg 11 mcg 15 mcg
Macrogol 400 — 555 mcg 400 — 797 mcg 400 — 1.128 mg

Vardenafil online: form of issue

The pharmacy Vardenafil online comes in the form of biconvex tablets, coated with a transparent coating and brand embossed concern. Their color varies from pale orange to orange with a mixture of gray. The embossing on one of the sides was made in the form of a figure indicating the dose of Vardenafil in a tablet (5, 10 or 20, respectively). On the other side — represented by the Bayer brand cross.

Tablets have a slightly rough surface and are almost tasteless. The form of their release is classic: a cardboard box with one blister of laminated aluminum foil and instructions for use. «Levitra coupon» inside. In the blister itself contains 1 or 4 tablets.

Contraindications

The main contraindications to the use of Vardenafil are:

  • Patient age less than 16 years;
  • Parallel intake of nitric oxide or nitrate donors;
  • Individual intolerance to Vardenafil or auxiliary elements «Levitra»;
  • Concurrent treatment with ritonavir, indinavir or other HIV protease inhibitors.
READ  How to choose Levitra or Sealex? Levitra reviews

Side effects

Like other drugs from the group of PDE5 inhibitors, «Levitra» — a potent drug, and therefore for an overdose (or if the pills simply do not fit him for medical reasons), the patient may experience the following side effects «Levitra».

The effectiveness of the drug Levitra for potency. Where to get Vardenafil online?
CNS Respiratory system Digestive system Organs of vision Bones and muscles Other
Drowsiness Dyspnea Dyspepsia Increased intraocular pressure Myalgia photosensitivity
Dizziness Rhinorrhea Nausea and vomiting Temporary visual impairment Back pain Allergic reactions
Headache Rhinitis Diarrhea Change in light sensitivity Increased muscle tone face swelling
Fainting Nose bleed Increased ALT and AST Impaired tearing Increased CPK Erection pain
Increased anxiety Swelling of the mucosa and larynx Stomach ache Priapism

 

In addition to the above-mentioned internal systems, a sharp increase in sexual activity can also adversely affect the heart.
The effectiveness of the drug Levitra for potency. Where to get Vardenafil online?

As a result, this can result in:

  • Sudden drops in blood pressure;
  • Orthostatic hypotension;
  • Appearance of angina pectoris;
  • Myocardial infarction and (in very rare cases) – death.
Therefore, if you decide to start taking Vardenafil online or are already taking it, but you want to change the dosage, do not forget to first consult with a cardiologist and other narrow specialists, as well as undergo an ECG and relevant examinations.

Special instructions for Vardenafil online

Like other medications to combat erectile disfunction, «Vardenafil online» It should be taken only on prescription and strictly under his supervision.

Otherwise, even a healthy person may experience:

  1. With deterioration of the cardiovascular system (due to excessive stress on the heart during sexual activity);
  2. With a sharp drop in blood pressure and the ensuing consequences (because the drug has a vasodilating effect);
  3. With transient loss of vision and non-arteritis ischemic neuropathy of the optic nerve;
  4. With emergencies and problems at work, since the reaction to the drug in patients driving vehicles and working with mechanisms in each individual case will be different.

Positive and negative qualities of the drug

Having carefully studied the reviews of doctors about «Levitra», as well as contraindications to its use and analogues, you can summarize the information obtained in the form of a pivot table.

Benefits «Levitra» disadvantages «Levitra»
Efficiency. The prevailing part of the patients speaks of the drug purely positively. High price. The effect after taking the pill lasts only a couple of hours, and therefore it is not affordable for many to regularly buy them.
No need to adjust the dose for the elderly and patients from a number of other problem groups. The presence of generics that have low efficiency and make anti-advertising «original» drug.
Extensive research in the field of interaction with other drugs and contraindications. An impressive number of side effects and contraindications.
Prescription leave, and therefore, the extra time that the patient must spend on recording and visiting a doctor.
READ  Levitra method of use. What is better: Levitra vs Viagra

Vardenafil interactions with other drugs

As you know, trouble never comes alone, and therefore many patients are forced to combine taking Vardenafil online and other medicines. If you find yourself in a similar situation, be sure to consult your doctor before starting the course and read the following information about the research on the topic of drug compatibility «Levitra».

So one-time intake with ritonavir, itraconazole and other strong inhibitors of the class CYP3A4 slows the withdrawal of Vardenafil from the body, as a result of which its concentration in the blood plasma increases significantly. For clarity:

  • Erythromycin in combination with «Levitra» provokes an increase in AUC (total daily concentration) Vardenafil in plasma 4 times and Cmax (maximum concentration) – 3 times.
  • Ketoconazole, which, by the way, also acts as a very potent inhibitor of CYP3A4, with one-time admission provokes an increase in Cmax Vardenafil — 4 times, and AUC – 10 times.
  • HIV protease indinavir contributes to an increase in AUC Vardenafil in blood 16 times (1500%), and Cmax — 7 times. But a day after taking both drugs, the concentration of this component is reduced to 4% of its maximum concentration.
  • Ritonavir, entering into a chemical reaction with «Levitra», blocks the liver metabolism of Vardenafil, increasing its concentration in the blood: total daily – 49 times, and the maximum – 13 times. In this case, the combination of drugs significantly increases the average time of action «Levitra» — up to 25-26 hours.

It is possible to combine Vardenafil with drugs from the group of alpha-blockers only if the patient’s blood pressure indicators are stable over the past six months.

In this case, the dosage of the first medicinal product should not exceed the minimum acceptable dose. – 5 mg / day.

Nifedipine in combination with Vardenafil online provokes a decrease in blood pressure: systolic – at 5.9 mm Hg. pillar and diastolic – at 5.2 mm Hg. pillar. In general medical practice, such indicators are characterized as «minor pharmacokinetic effect». However, people with hypersensitivity do not hurt to take this information into service.

As to the drugs, which, according to studies, do not affect the daily and maximum concentration of Vardenafil, they can include:

  1. «Warfarin». When taking up to 25 mg of this drug in combination with «Levitra» effects on prothrombin time (an indicator of the external pathway of blood clotting) and coagulation factors were not identified.
  2. «Glibenclamide» – but only if the dose of glyburide does not exceed 3.5 mg, as there is no reliable information on a higher dosage in the network.
  3. «Digoxin» does not provoke negative reactions in the body when taken at once with «Levitra» (provided that its dose does not exceed 0.375 mg).
  4. «Maalox» with a single dose, it does not affect the blood content of Vardenafil. Prolonged joint medication can cause weakness and general malaise.
  5. «Ranitidine» and other histamine H blockers2-receptors on bioavailability and clearance of components «Levitra» do not affect.
  6. «Cimetidine» – an inhibitor of cytochrome isoenzymes P450, per day of which you can take no more than 400 mg 2 times.
READ  All information about the drug for men Levitra. Viagra vs Levitra Battle

The list of neutrals with respect to Vardenafil can be supplemented with: acetylsalicylic acid, beta-blockers, numerous diuretics and hypoglycemic agents, ACE inhibitors, weak inhibitors of CYP3A4, and even ethanol. But only if the correct dosage of both drugs is selected.

Research on the combined effects on the body «Levitra» and other means against erectile disfunction has not been carried out. Therefore, taking them at the same time, you act at your own risk.

Instructions for use

Vardenafil online should be taken orally: about half an hour or an hour before the planned sexual act. The dosage of the drug should not exceed 10 mg at a time, and the frequency of administration – once a day. The desired effect is achieved only if the patient receives significant sexual stimulation.

As for the relationship of dosage and effectiveness, then:

  1. If the patient does not have the desired effect, the dosage can be increased by 2 times. – up to 20 mg / day.
  2. With the appearance of side effects – reduce to 5 mg / day.
  3. Older people (over 65) do not need a separate dose adjustment.
  4. Patients with hepatic insufficiency do not need a dose adjustment, but their initial dosage should not be 10 mg / day, but only 5 mg / day. In the future, it can be increased to 10 mg / day. or even up to 20 mg / day, but only after the approval of the doctor in whom the patient is being observed.
  5. Patients who have impaired renal function do not require a separate dose adjustment.

Leave a Reply

Your email address will not be published. Required fields are marked *